Leibniz Prize awarded to Ana Pombo

11.12.2024

The German Research Foundation (DFG) announced on December 11 that biochemist Ana Pombo from the Max Delbrück Center is among this year’s winners of the Gottfried Wilhelm Leibniz Prize. The Leibniz Prize is Germany’s most important research funding award and comes with a grant of €2.5 million.

A DNA strand, which is two meters long, is carefully folded within a cell nucleus only ten micrometers in diameter. This folding creates a spatial interplay between genes and their regulatory elements. Professor Ana Pombo seeks to understand how environmental factors and experiences influence this three-dimensional interplay and how diseases such as autism or epilepsy can arise. Her research group at the Berlin Institute for Medical Systems Biology of the Max Delbrück Center (MDC-BIMSB) develops new tools to better understand this fundamental mechanism. In 2017, her team published a method in the journal “Nature” that can map the 3D structure of entire genomes.
For her groundbreaking work, the primary committee of the German Research Foundation (DFG) decided to honor Ana Pombo and nine other scientists with Germany’s most significant research funding award. She will receive the Gottfried Wilhelm Leibniz Prize at a ceremonial event on March 19, 2025. The prize comes with a grant of €2.5 million.

“We aim to reverse disease-causing cellular changes as early as possible in the future. To achieve this, we first need to decode the mechanisms that, like a complex clockwork, determine how our genome functions,” says Professor Maike Sander, Scientific Director of the Max Delbrück Center. “Ana Pombo’s work makes a fundamental contribution to this goal. She is a true pioneer. We warmly congratulate her.” 

About Ana Pombo

Ana Pombo was born in 1969 in Portugal and studied biochemistry at the University of Lisbon. After completing her doctorate at the University of Oxford, she initially worked as a group leader at the MRC London Institute of Medical Sciences at Imperial College London, U.K. In 2013, she joined the Max Delbrück Center and simultaneously took on a professorship in Transcriptional Regulation and Genome Architecture at Humboldt University in Berlin. She is the Deputy Director of MDC-BIMSB and Deputy Program Spokesperson for the Max Delbrück Center. In 2007, she received the Robert Feulgen Prize and is a member of the European Molecular Biology Organization (EMBO) and the European Academy of Sciences.

Ana Pombo joins two previous winners at the Max Delbrück Center: Professor Nikolaus Rajewsky and Professor Carmen Birchmeier. Since 1985, the DFG has been honoring outstanding top researchers with the Leibniz Prize. The award provides recipients with opportunities to expand their research and hire highly qualified early-career scientists. The 2025 Leibniz Prizes will be presented in a ceremony on March 19, 2025, in Berlin. The award ceremony will be preceded by an event celebrating the 40th anniversary of the program, where all previous prize recipients will be able to connect and network.

Source: Press Release MDC
Press Release DFG

Contact:
Ana Pombo
Group Leader
NeuroCure PI
Max-Delbrück-Centrum für Molekulare Medizin (MDC)
Hannoversche Straße 28
10115 Berlin, Deutschland

Ana Pombo Lab

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