Lifestyle: The impact of lifestyle factors on the brain

Study Description:
Previous findings suggest that a healthy lifestyle can help reduce the risk of age-related diseases. In addition to smoking, alcohol consumption, weight and social interaction, special importance has been attributed to physical activity and nutrition. The direct impact of these influences on human cognition is, however, unclear, as are the underlying mechanisms.

This group investigated in various intervention studies (Project 1: Improving the brain through diet in elderly individuals; Project 2: Improving the brain through a combination of diet, exercise and cognitive stimulation in elderly individuals with existing Mild Cognitive Impairment MCI) the impact of exercise and healthy eating habits (including calorie restriction and omega-3 fatty acids) on the aging brain. For this we used, neuropsychological tests, analysis of peripheral biomarkers in the blood, and imaging techniques such as structural and functional magnetic resonance imaging (MRI).

Principle Investigator: Prof. Dr. Agnes Flöel (WG Cognitive Neurology, NCRC, CSB, Neurology CCM)

Course of the study (Project 2): 07/2013 - 05/2014

Bohlken, J., T. Kobe, L. M. Dietz, M. A. Rapp, T. Kohlmann, and A. Floel. "[Differences in Attitudes of Patients with Mild Cognitive Impairment Towards Early Diagnosis at a University Clinic and a Specialist Physician's Office]." Fortschr Neurol Psychiatr 83, no. 10 (Oct 2015): 563-7.  Link