REPABO: Patient-based measuring instruments in multiple sclerosis

Study Description:
Good measuring instruments are necessary to describe the benefits and harms of various therapies, whether for symptom relief or influence on the MS itself. Currently, the main standard accepted worldwide is the EDSS, the Expanded Disability Status Scale. The aim of this study was to examine patient-based investigation instruments, especially questionnaires and new objective tests, in particular a walking endurance test and eyesight check. We examined to what extent these tools show the activity of the disease better than traditionally used instruments. Participation was open to patients with high disease activity, as well as patients without relapses and without an increase in EDSS in the last two years. Patients were visited every three months in the outpatient clinic for various tests and examinations

Principle Investigator: Prof. Dr. Friedemann Paul (WG Clinical Neuroimmunology, NCRC, ECRC)

Course of the study: 01/2012 - 11/2013