SysBio lectures: RNA Biology and Disease: Florian Heyd
Speaker: Florian Heyd (FU Berlin)
Title: Body temperature cycles control alternative splicing inmammals: mechanism and functional implications
Date: Wednesday, November 29th 2017, 09:30 - 10:30 am
Location: MDC.C Conference Center, Dendrit 2/3, Robert-Rössle-Str. 10, 13125 Berlin
Research Summary
The Heyd lab address the fundamental question how alternative splicing regulates cellular function and identity; their main model systems are the mammalian circadian clock and T cell activation. In addition to its functionality they investigate mechanisms behind signal-induced, cell type specific and circadian alternative splicing. Furthermore, comparing splicing patterns between different species led to their interest in connecting alternative splicing and evolution. They employ a variety of techniques ranging from bioinformatics to RNA-protein interaction assays, in vitro splicing, minigenes and cell culture and mouse models.
For more information on Florian Heyd's work, take a look at the lab’s website here: http://www.bcp.fu-berlin.de/en/chemie/biochemie/research-groups/heyd-group/research/index.html