Ausgewählte Publikationen
2024
Arlt, Friederike A., Ramona Miske, Marie-Luise Machule, Peter Broegger Christensen, Swantje Mindorf, Bianca Teegen, Kathrin Borowski, Maria Buthut, Rosa Rößling, Elisa Sánchez-Sendín, Scott van Hoof, César Cordero-Gómez, Isabel Bünger, Helena Radbruch, Andrea Kraft, Ilya Ayzenberg, Jaqueline Klausewitz, Niels Hansen, Charles Timäus, Peter Körtvelyessy, Thomas Postert, Kirsten Baur-Seack, Constanze Rost, Robert Brunkhorst, Kathrin Doppler, Niklas Haigis, Gerhard Hamann, Albrecht Kunze, Alexandra Stützer, Matthias Maschke, Nico Melzer, Felix Rosenow, Kai Siebenbrodt, Christian Stenør, Martin Dichgans, Marios K. Georgakis, Rong Fang, Gabor C. Petzold, Michael Görtler, Inga Zerr, Silke Wunderlich, Ivan Mihaljevic, Paul Turko, Marianne Schmidt Ettrup, Emilie Buchholz, Helle Foverskov Rasmussen, Mahoor Nasouti, Ivan Talucci, Hans M. Maric, Stefan H. Heinemann, Matthias Endres, Demdas study group, Lars Komorowski, and Harald Prüss. "Kcna2 Igg Autoimmunity in Neuropsychiatric Diseases." Brain Behavior and Immunity 117 (2024): 399-411. Accessed 2024/02/22. https://dx.doi.org/10.1016/j.bbi.2024.01.220.
Bär J, Fanutza T, Reimann CC, Seipold L, Grohe M, Bolter JR, Delfs F, Bucher M, Gee CE, Schweizer M, Saftig P, Mikhaylova M. . "Non-Canonical Function of Adam10 in Presynaptic Plasticity." Cellular and Molecular Life Sciences 81, no. 1 (2024): 342. Accessed 2024/08/21. https://dx.doi.org/10.1007/s00018-024-05327-8.
Carretero-Guillén, Alejandro, Mario Treviño, María Ángeles Gómez-Climent, Godwin K. Dogbevia, Ilaria Bertocchi, Rolf Sprengel, Matthew E. Larkum, Andreas Vlachos, Agnès Gruart, José M. Delgado-García, and Mazahir T. Hasan. "Dentate Gyrus Is Needed for Memory Retrieval." Molecular Psychiatry (2024): 1-12. Accessed 2024/05/03. https://dx.doi.org/10.1038/s41380-024-02546-0.
Cazale-Debat, L., L. Scheunemann, M. Day, D. V. Alquicira T. Fernandez, A. Dimtsi, Y. Zhang, L. A. Blackburn, C. Ballardini, K. Greenin-Whitehead, E. Reynolds, A. C. Lin, D. Owald, and C. Rezaval. "Mating Proximity Blinds Threat Perception." Nature (Aug 28 2024). https://dx.doi.org/10.1038/s41586-024-07890-3.
Cerda-Jara, Cledi A., Seung Joon Kim, Gwendolin Thomas, Zohreh Farsi, Grygoriy Zolotarov, Giuliana Dube, Aylina Deter, Ella Bahry, Elisabeth Georgii, Andrew Woehler, Monika Piwecka, and Nikolaus Rajewsky. "Mir-7 Controls Glutamatergic Transmission and Neuronal Connectivity in a Cdr1as-Dependent Manner." Embo Reports (2024): 1-32. Accessed 2024/06/26. https://dx.doi.org/10.1038/s44319-024-00168-9.
Cook, Vano, A. H. Groneberg, M. Hoffmann, M. Kadobianskyi, J. Veith, L. Schulze, J. Henninger, R. Britz, and B. Judkewitz. "Ultrafast Sound Production Mechanism in One of the Smallest Vertebrates." Proc Natl Acad Sci U S A 121, no. 10 (Mar 5 2024): e2314017121. https://dx.doi.org/10.1073/pnas.2314017121.
Fei, Lu, Yongtian Liang, Ulrich Kintscher, and Stephan J. Sigrist. "Coupling of Mitochondrial State with Active Zone Plasticity in Early Brain Aging." Redox Biology 79 (2024): 103454. Accessed 2024/12/20. https://dx.doi.org/10.1016/j.redox.2024.103454.
Roxanne, Lofredi, K. Feldmann Lucia, Krause Patricia, Scheller Ute, Neumann Wolf-Julian, K. Krauss Joachim, Saryyeva Assel, Schneider Gerd-Helge, Faust Katharina, Sander Tilmann, and A. Kühn Andrea. "Striato-Pallidal Oscillatory Connectivity Correlates with Symptom Severity in Dystonia Patients." Nature Communications 15, no. 1 (2024): 8475. Accessed 2024/10/29. https://dx.doi.org/10.1038/s41467-024-52814-4.
Nolte, Christian H., Regina von Rennenberg, Simon Litmeier, David M. Leistner, Kristina Szabo, Stefan Baumann, Annerose Mengel, Dominik Michalski, Timo Siepmann, Stephan Blankenberg, Gabor C. Petzold, Martin Dichgans, Hugo Katus, Burkert Pieske, Vera Regitz-Zagrosek, Tim Bastian Braemswig, Ida Rangus, Amra Pepic, Eik Vettorazzi, Andreas M. Zeiher, Jan F. Scheitz, Karl Wegscheider, Ulf Landmesser, and Matthias Endres. "Type 1 Myocardial Infarction in Patients with Acute Ischemic Stroke." Jama Neurology 81, no. 7 (2024). Accessed 2024/06/10. https://dx.doi.org/10.1001/jamaneurol.2024.1552.
Peng, Yangfan, Antje Bjelde, Pau Vilimelis Aceituno, Franz X. Mittermaier, Henrike Planert, Sabine Grosser, Julia Onken, Katharina Faust, Thilo Kalbhenn, Matthias Simon, Helena Radbruch, Pawel Fidzinski, Dietmar Schmitz, Henrik Alle, Martin Holtkamp, Imre Vida, Benjamin F. Grewe, and Jörg R. P. Geiger. "Directed and Acyclic Synaptic Connectivity in the Human Layer 2-3 Cortical Microcircuit." Science 384, no. 6693 (2024): 338-43. Accessed 2024/05/21. https://dx.doi.org/10.1126/science.adg8828.
Pentimalli, T. M., N. Karaiskos, and N. Rajewsky. "Challenges and Opportunities in the Clinical Translation of High-Resolution Spatial Transcriptomics." Annu Rev Pathol (Oct 30 2024). https://dx.doi.org/10.1146/annurev-pathmechdis-111523-023417.
Sammons, Rosanna P., Mourat Vezir, Laura Moreno-Velasquez, Gaspar Cano, Marta Orlando, Meike Sievers, Eleonora Grasso, Verjinia D. Metodieva, Richard Kempter, Helene Schmidt, and Dietmar Schmitz. "Structure and Function of the Hippocampal Ca3 Module." Proceedings of the National Academy of Sciences of the United States of America 121, no. 6 (2024): e2312281120. Accessed 2024/02/12. https://dx.doi.org/10.1073/pnas.2312281120.
Schott, Marie, Daniel León-Periñán, Elena Splendiani, Leon Strenger, Jan Robin Licha, Tancredi Massimo Pentimalli, Simon Schallenberg, Jonathan Alles, Sarah Samut Tagliaferro, Anastasiya Boltengagen, Sebastian Ehrig, Stefano Abbiati, Steffen Dommerich, Massimiliano Pagani, Elisabetta Ferretti, Giuseppe Macino, Nikos Karaiskos, and Nikolaus Rajewsky. "Open-St: High-Resolution Spatial Transcriptomics in 3d." Cell (2024). Accessed 2024/07/04. https://dx.doi.org/10.1016/j.cell.2024.05.055.
Estelle, Toulmé, Lázaro Andrea Salazar, Trimbuch Thorsten, Rizo Josep, and Rosenmund Christian. "Neurotransmitter Release Is Triggered by a Calcium-Induced Rearrangement in the Synaptotagmin-1/Snare Complex Primary Interface." Proceedings of the National Academy of Sciences of the United States of America 121, no. 42 (2024): e2409636121. Accessed 2024/10/29. https://dx.doi.org/10.1073/pnas.2409636121.
Tancredi Massimo, Pentimalli, Karaiskos Nikos, and Rajewsky Nikolaus. "Challenges and Opportunities in the Clinical Translation of High-Resolution Spatial Transcriptomics." Annual Review of Pathology Mechanisms of Disease (2024). Accessed 2024/11/15. https://dx.doi.org/10.1146/annurev-pathmechdis-111523-023417.
Veith, Johannes, Thomas Chaigne, Ana Svanidze, Lena Elisa Dressler, Maximilian Hoffmann, Ben Gerhardt, and Benjamin Judkewitz. "The Mechanism for Directional Hearing in Fish." Nature (2024): 1-7. Accessed 2024/07/04. https://dx.doi.org/10.1038/s41586-024-07507-9.
Willemin, Andréa, Dominik Szabó, and Ana Pombo. "Epigenetic Regulatory Layers in the 3d Nucleus." Molecular Cell (2024). Accessed 2024/02/02. https://dx.doi.org/10.1016/j.molcel.2023.12.032.
2023
Beagrie, R. A., C. J. Thieme, C. Annunziatella, C. Baugher, Y. Zhang, M. Schueler, A. Kukalev, R. Kempfer, A. M. Chiariello, S. Bianco, Y. Li, T. Davis, A. Scialdone, L. R. Welch, M. Nicodemi, and A. Pombo. "Multiplex-Gam: Genome-Wide Identification of Chromatin Contacts Yields Insights Overlooked by Hi-C." Nat Methods (Jun 19 2023). https://dx.doi.org/10.1038/s41592-023-01903-1.
Bolz, Svenja, Natalie Kaempf, Dmytro Puchkov, Michael Krauss, Giulia Russo, Tolga Soykan, Christopher Schmied, Martin Lehmann, Rainer Müller, Carsten Schultz, David Perrais, Tanja Maritzen, and Volker Haucke. "Synaptotagmin 1-Triggered Lipid Signaling Facilitates Coupling of Exo- and Endocytosis." Neuron (2023). Accessed 2023/10/16. https://dx.doi.org/10.1016/j.neuron.2023.08.016.
Gerhardt, Ben, Kristin Klaue, Lennart Eigen, Jutta Schwarz, Stefan Hecht, and Michael Brecht. "Dii-Ct—a Bimodal Neural Tracer for X-Ray and Fluorescence Imaging." Cell Reports Methods (2023): 100486. Accessed 2023/06/26. https://dx.doi.org/10.1016/j.crmeth.2023.100486.
Ghelani, T., M. Escher, U. Thomas, K. Esch, J. Lutzkendorf, H. Depner, M. Maglione, P. Parutto, S. Gratz, T. Matkovic-Rachid, S. Ryglewski, A. M. Walter, D. Holcman, K. O'Connor Giles, M. Heine, and S. J. Sigrist. "Interactive Nanocluster Compaction of the Elks Scaffold and Cacophony Ca(2+) Channels Drives Sustained Active Zone Potentiation." Sci Adv 9, no. 7 (Feb 17 2023): eade7804. https://dx.doi.org/10.1126/sciadv.ade7804.
Hao, Y., E. Toulme, B. Konig, C. Rosenmund, and A. J. R. Plested. "Targeted Sensors for Glutamatergic Neurotransmission." Elife 12 (Jan 9 2023). https://dx.doi.org/10.7554/eLife.84029.
Hoffmann, M., J. Henninger, J. Veith, L. Richter, and B. Judkewitz. "Blazed Oblique Plane Microscopy Reveals Scale-Invariant Inference of Brain-Wide Population Activity." Nat Commun 14, no. 1 (Dec 4 2023): 8019. https://dx.doi.org/10.1038/s41467-023-43741-x.
Knierim, E., J. Vogt, M. Kintscher, A. Ponomarenko, J. Baumgart, P. Beed, T. Korotkova, T. Trimbuch, A. Panzer, O. K. Steinlein, U. Stephani, A. Escayg, M. Koko, Y. Liu, H. Lerche, D. Schmitz, R. Nitsch, and M. Schuelke. "Mutations in Plasticity-Related-Gene-1 (Prg-1) Protein Contribute to Hippocampal Seizure Susceptibility and Modify Epileptic Phenotype." Cereb Cortex (Mar 28 2023). https://dx.doi.org/10.1093/cercor/bhad051.
Legnini, Ivano, Lisa Emmenegger, Alessandra Zappulo, Agnieszka Rybak-Wolf, Ricardo Wurmus, Anna Oliveras Martinez, Cledi Cerda Jara, Anastasiya Boltengagen, Talé Hessler, Guido Mastrobuoni, Stefan Kempa, Robert Zinzen, Andrew Woehler, and Nikolaus Rajewsky. "Spatiotemporal, Optogenetic Control of Gene Expression in Organoids." Nature Methods 20, no. 10 (2023): 1544-52. Accessed 2023/10/16. https://dx.doi.org/10.1038/s41592-023-01986-w.
Liu, H. Y., R. Arsie, D. Schwabe, M. Schilling, I. Minia, J. Alles, A. Boltengagen, C. Kocks, M. Falcke, N. Friedman, M. Landthaler, and N. Rajewsky. "Slam-Drop-Seq Reveals Mrna Kinetic Rates Throughout the Cell Cycle." Molecular Systems Biology (Aug 28 2023). https://dx.doi.org/ARTN e1142710.15252/msb.202211427.
Lowenstein, Elijah D., Pierre-Louis Ruffault, Aristotelis Misios, Kate L. Osman, Huimin Li, Rachel S. Greenberg, Rebecca Thompson, Kun Song, Stephan Dietrich, Xun Li, Nikita Vladimirov, Andrew Woehler, Jean-François Brunet, Niccolò Zampieri, Ralf Kühn, Stephen D. Liberles, Shiqi Jia, Gary R. Lewin, Nikolaus Rajewsky, Teresa E. Lever, and Carmen Birchmeier. "Prox2 and Runx3 Vagal Sensory Neurons Regulate Esophageal Motility." Neuron (2023). Accessed 2023/06/26. https://dx.doi.org/10.1016/j.neuron.2023.04.025.
Meinhardt, Jenny, Simon Streit, Carsten Dittmayer, Regina v Manitius, Helena Radbruch, and Frank L. Heppner. "The Neurobiology of Sars-Cov-2 Infection." Nature Reviews Neuroscience (2023): 1-13. Accessed 2023/12/14. https://dx.doi.org/10.1038/s41583-023-00769-8.
Reincke, S. Momsen, Niels von Wardenburg, Marie A. Homeyer, Hans-Christian Kornau, Gregorio Spagni, Lucie Y. Li, Jakob Kreye, Elisa Sánchez-Sendín, Sonja Blumenau, Dominik Stappert, Helena Radbruch, Anja E. Hauser, Annette Künkele, Inan Edes, Dietmar Schmitz, and Harald Prüss. "Chimeric Autoantibody Receptor T cells Deplete Nmda Receptor-Specific B Cells." Cell 186, no. 23 (2023): 5084-97.e18. Accessed 2023/11/24. https://dx.doi.org/10.1016/j.cell.2023.10.001.
Rizalar, Filiz Sila, Max T. Lucht, Astrid Petzoldt, Shuhan Kong, Jiachen Sun, James H. Vines, Narasimha Swamy Telugu, Sebastian Diecke, Thomas Kaas, Torsten Bullmann, Christopher Schmied, Delia Löwe, Jason S. King, Wonhwa Cho, Stefan Hallermann, Dmytro Puchkov, Stephan J. Sigrist, and Volker Haucke. "Phosphatidylinositol 3,5-Bisphosphate Facilitates Axonal Vesicle Transport and Presynapse Assembly." Science 382, no. 6667 (2023): 223-30. Accessed 2023/11/06. https://dx.doi.org/10.1126/science.adg1075.
Schnell, S., E. Knierim, P. Bittigau, J. Kreye, K. Hauptmann, P. Hundsdoerfer, S. Morales-Gonzalez, M. Schuelke, and M. Nikolaus. "Hodgkin Lymphoma Cell Lines and Tissues Express Mglur5: A Potential Link to Ophelia Syndrome and Paraneoplastic Neurological Disease." Cells 12, no. 4 (Feb 13 2023). https://dx.doi.org/10.3390/cells12040606.
Sigrist, Stephan J., and Volker Haucke. "Orchestrating Vesicular and Nonvesicular Membrane Dynamics by Intrinsically Disordered Proteins." Embo Reports (2023): e57758. Accessed 2023/10/16. https://dx.doi.org/10.15252/embr.202357758.
Tzilivaki, A., J. J. Tukker, N. Maier, P. Poirazi, R. P. Sammons, and D. Schmitz. "Hippocampal Gabaergic Interneurons and Memory." Neuron (Jul 14 2023). https://dx.doi.org/10.1016/j.neuron.2023.06.016.
Urzi, A., I. Lahmann, L. V. N. Nguyen, B. R. Rost, A. Garcia-Perez, N. Lelievre, M. E. Merritt-Garza, H. C. Phan, G. J. Bassell, W. Rossoll, S. Diecke, S. Kunz, D. Schmitz, and M. Gouti. "Efficient Generation of a Self-Organizing Neuromuscular Junction Model from Human Pluripotent Stem Cells." Nat Commun 14, no. 1 (Dec 19 2023): 8043. https://dx.doi.org/10.1038/s41467-023-43781-3.
Viana da Silva, Silvia, Matthias G. Haberl, Kshitij Gaur, Rina Patel, Gautam Narayan, Max Ledakis, Maylin L. Fu, Miguel de Castro Vieira, Edward H. Koo, Jill K. Leutgeb, and Stefan Leutgeb. "Localized App Expression Results in Progressive Network Dysfunction by Disorganizing Spike Timing." Neuron (2023). Accessed 2023/11/06. https://dx.doi.org/10.1016/j.neuron.2023.10.001.
Vollweiter, D., J. K. Shergill, A. Hilse, G. Kochlamazashvili, S. P. Koch, S. Mueller, P. Boehm-Sturm, V. Haucke, and T. Maritzen. "Intersectin Deficiency Impairs Cortico-Striatal Neurotransmission and Causes Obsessive-Compulsive Behaviors in Mice." Proc Natl Acad Sci U S A 120, no. 35 (Aug 29 2023): e2304323120. https://dx.doi.org/10.1073/pnas.2304323120.
Zhang, Bing, Sensen Zhang, Maya M. Polovitskaya, Jingbo Yi, Binglu Ye, Ruochong Li, Xueying Huang, Jian Yin, Sebastian Neuens, Tom Balfroid, Julie Soblet, Daphné Vens, Alec Aeby, Xiaoling Li, Jinjin Cai, Yingcai Song, Yuanxi Li, Marco Tartaglia, Yang Li, Thomas J. Jentsch, Maojun Yang, and Zhiqiang Liu. "Molecular Basis of Clc-6 Function and Its Impairment in Human Disease." Science Advances 9, no. 41 (2023): eadg4479. Accessed 2023/11/06. https://dx.doi.org/10.1126/sciadv.adg4479.
Zolnik, T. A., A. Bronec, A. Ross, M. Staab, R. N. S. Sachdev, Z. Molnar, B. J. Eickholt, and M. E. Larkum. "Layer 6b Controls Brain State Via Apical Dendrites and the Higher-Order Thalamocortical System." Neuron (Dec 11 2023). https://dx.doi.org/10.1016/j.neuron.2023.11.021.
2022
Andrzejak, E., E. Rabinovitch, J. Kreye, H. Pruss, C. Rosenmund, N. E. Ziv, C. C. Garner, and F. Ackermann. "Patient-Derived Anti-Nmdar Antibody Disinhibits Cortical Neuronal Networks through Dysfunction of Inhibitory Neuron Output." J Neurosci (Mar 2 2022). https://dx.doi.org/10.1523/JNEUROSCI.1689-21.2022.
Arends, C. M., T. G. Liman, P. M. Strzelecka, A. Kufner, P. Lowe, S. Huo, C. M. Stein, S. K. Piper, M. Tilgner, P. S. Sperber, S. Dimitriou, P. Heuschmann, R. Hablesreiter, C. Harms, L. Bullinger, J. E. Weber, M. Endres, and F. Damm. "Associations of Clonal Haematopoiesis with Recurrent Vascular Events and Death in Patients with Incident Ischemic Stroke." Blood (Nov 28 2022). https://dx.doi.org/10.1182/blood.2022017661.
Aschman, T., R. Mothes, F. L. Heppner, and H. Radbruch. "What Sars-Cov-2 Does to Our Brains." Immunity 55, no. 7 (Jul 12 2022): 1159-72. https://dx.doi.org/10.1016/j.immuni.2022.06.013.
Fernandez Lahore, R. G., N. P. Pampaloni, E. Peter, M. M. Heim, L. Tillert, J. Vierock, J. Oppermann, J. Walther, D. Schmitz, D. Owald, A. J. R. Plested, B. R. Rost, and P. Hegemann. "Calcium-Permeable Channelrhodopsins for the Photocontrol of Calcium Signalling." Nat Commun 13, no. 1 (Dec 21 2022): 7844. https://dx.doi.org/10.1038/s41467-022-35373-4.
Gidon, A., J. Aru, and M. E. Larkum. "Does Brain Activity Cause Consciousness? A Thought Experiment." Plos Biology 20, no. 6 (Jun 2022). https://dx.doi.org/ARTN e3001651 10.1371/journal.pbio.3001651.
Hesse, J., J. H. Schleimer, N. Maier, D. Schmitz, and S. Schreiber. "Temperature Elevations Can Induce Switches to Homoclinic Action Potentials That Alter Neural Encoding and Synchronization." Nat Commun 13, no. 1 (Jul 8 2022): 3934. https://dx.doi.org/10.1038/s41467-022-31195-6.
Horn, A., M. M. Reich, S. Ewert, N. Li, B. Al-Fatly, F. Lange, J. Roothans, S. Oxenford, I. Horn, S. Paschen, J. Runge, F. Wodarg, K. Witt, R. C. Nickl, M. Wittstock, G. H. Schneider, P. Mahlknecht, W. Poewe, W. Eisner, A. K. Helmers, C. Matthies, J. K. Krauss, G. Deuschl, J. Volkmann, and A. A. Kuhn. "Optimal Deep Brain Stimulation Sites and Networks for Cervical Vs. Generalized Dystonia." Proc Natl Acad Sci U S A 119, no. 14 (Apr 5 2022): e2114985119. https://dx.doi.org/10.1073/pnas.2114985119.
Huang, S., C. Piao, C. B. Beuschel, Z. Zhao, and S. J. Sigrist. "A Brain-Wide Form of Presynaptic Active Zone Plasticity Orchestrates Resilience to Brain Aging in Drosophila." PLoS Biol 20, no. 12 (Dec 2022): e3001730. https://dx.doi.org/10.1371/journal.pbio.3001730.
Imoto, Yuuta, Sumana Raychaudhuri, Ye Ma, Pascal Fenske, Eduardo Sandoval, Kie Itoh, Eva-Maria Blumrich, Hideaki T. Matsubayashi, Lauren Mamer, Fereshteh Zarebidaki, Berit Söhl-Kielczynski, Thorsten Trimbuch, Shraddha Nayak, Janet H. Iwasa, Jian Liu, Bin Wu, Taekjip Ha, Takanari Inoue, Erik M. Jorgensen, Michael A. Cousin, Christian Rosenmund, and Shigeki Watanabe. "Dynamin Is Primed at Endocytic Sites for Ultrafast Endocytosis." Neuron (2022). Accessed 2022/08/22. https://dx.doi.org/10.1016/j.neuron.2022.06.010.
Lipstein, N. "Mechanism Underlying a Risk Gene in Neurodegeneration" Nature 603, no. 7899 (Mar 3 2022): 1-2. <Go to ISI>://WOS:000762310800002. https://doi.org/10.1038/d41586-022-00383-1.
Nikolaus, M., A. Koch, W. Stenzel, S. Elezkurtaj, F. Sahm, A. Tietze, L. Stoffler, J. Kreye, P. H. Driever, U. W. Thomale, A. M. Kaindl, M. Schuelke, and E. Knierim. "Atypical Nmda Receptor Expression in a Diffuse Astrocytoma, Myb- or Mybl1-Altered as a Trigger for Autoimmune Encephalitis." Acta Neuropathologica 144, no. 2 (Aug 2022): 385-89. https://dx.doi.org/10.1007/s00401-022-02447-y.
Nitzan, N., R. Swanson, D. Schmitz, and G. Buzsaki. "Brain-Wide Interactions During Hippocampal Sharp Wave Ripples." Proc Natl Acad Sci U S A 119, no. 20 (May 17 2022): e2200931119. https://dx.doi.org/10.1073/pnas.2200931119.
Patzke, Christopher, Jinye Dai, Marisa M. Brockmann, Zijun Sun, Pascal Fenske, Christian Rosenmund, and Thomas C. Südhof. "Cb1 Receptor Activation Rapidly Alters Synaptic Vesicle Numbers in Mouse Hippocampal Synapses." Molecular Psychiatry 26, no. 11 (6103-03. Accessed 2022/08/22. https://dx.doi.org/10.1038/s41380-021-01426-1.
Posor, Y., W. Jang, and V. Haucke. "Phosphoinositides as Membrane Organizers." Nature Reviews Molecular Cell Biology (May 19 2022). https://dx.doi.org/10.1038/s41580-022-00490-x.
Roediger, J., T. A. Dembek, J. Achtzehn, J. L. Busch, A. P. Kramer, K. Faust, G. H. Schneider, P. Krause, A. Horn, and A. A. Kuhn. "Automated Deep Brain Stimulation Programming Based on Electrode Location: A Randomised, Crossover Trial Using a Data-Driven Algorithm." Lancet Digit Health (Dec 15 2022). https://dx.doi.org/10.1016/S2589-7500(22)00214-X.
Rohmann, J. L., M. Piccininni, M. Ebinger, M. Wendt, J. E. Weber, E. Schwabauer, F. Geisler, E. Freitag, P. Harmel, I. Lorenz-Meyer, I. Rohrpasser-Napierkowski, C. H. Nolte, D. G. Nabavi, I. Schmehl, A. Ekkernkamp, M. Endres, and H. J. Audebert. "Effect of Mobile Stroke Unit Dispatch in All Patients with Acute Stroke or Tia." Ann Neurol (Oct 30 2022). https://dx.doi.org/10.1002/ana.26541.
Rost, B. R., J. Wietek, O. Yizhar, and D. Schmitz. "Optogenetics at the Presynapse." Nat Neurosci 25, no. 8 (Aug 2022): 984-98. https://dx.doi.org/10.1038/s41593-022-01113-6.
Sztanka-Toth, Tamas Ryszard, Marvin Jens, Nikos Karaiskos, and Nikolaus Rajewsky. "Spacemake: Processing and Analysis of Large-Scale Spatial Transcriptomics Data." GigaScience 11 (2022): giac064. Accessed 2022/08/22. https://dx.doi.org/10.1093/gigascience/giac064.
Turrel, O., N. Ramesh, M. J. F. Escher, A. Pooryasin, and S. J. Sigrist. "Transient Active Zone Remodeling in the Drosophila Mushroom Body Supports Memory." Curr Biol (Oct 30 2022). https://dx.doi.org/10.1016/j.cub.2022.10.017.
Tzilivaki, A., N. Maier, and D. Schmitz. "Interneuron Switching on and Off across Memory Rhythms." Neuron 110, no. 12 (Jun 15 2022): 1884-86. https://dx.doi.org/10.1016/j.neuron.2022.05.019.
van Rheede, J. J., L. K. Feldmann, J. L. Busch, J. E. Fleming, V. Mathiopoulou, T. Denison, A. Sharott, and A. A. Kuhn. "Diurnal Modulation of Subthalamic Beta Oscillatory Power in Parkinson's Disease Patients During Deep Brain Stimulation." NPJ Parkinsons Dis 8, no. 1 (Jul 8 2022): 88. https://dx.doi.org/10.1038/s41531-022-00350-7.
Vardar, G., A. Salazar-Lazaro, S. Zobel, T. Trimbuch, and C. Rosenmund. "Syntaxin-1a Modulates Vesicle Fusion in Mammalian Neurons Via Juxtamembrane Domain Dependent Palmitoylation of Its Transmembrane Domain." Elife 11 (May 31 2022). https://dx.doi.org/ARTN e78182 10.7554/eLife.78182.
Wang, C., M. M. Polovitskaya, B. D. Delgado, T. J. Jentsch, and S. B. Long. "Gating Choreography and Mechanism of the Human Proton-Activated Chloride Channel Asor." Sci Adv 8, no. 5 (Feb 4 2022): eabm3942. https://dx.doi.org/10.1126/sciadv.abm3942.
Zeziulia, M., S. Blin, F. W. Schmitt, M. Lehmann, and T. J. Jentsch. "Proton-Gated Anion Transport Governs Macropinosome Shrinkage." Nat Cell Biol 24, no. 6 (Jun 2022): 885-95. https://dx.doi.org/10.1038/s41556-022-00912-0.
2021
Bespalov, Anton, René Bernard, Anja Gilis, Björn Gerlach, Javier Guillen, Vincent Castagne, Isabel Lefevre, Fiona Ducrey, Lee Monk, Sandrine Bongiovanni, Bruce Altevogt, Maria Arroyo Araujo, Lior Bikovski, Natasja de Bruin, Esmeralda Castaños-Vélez, Alexander Dityatev, Christoph H. Emmerich, Raafat Fares, Chantelle Ferland-Beckham, Christelle Froger-Colléaux, Valerie Gailus-Durner, Sabine M. Hölter, Martine C. J. Hofmann, Patricia Kabitzke, Martien J. H. Kas, Claudia Kurreck, Paul Moser, Malgorzata Pietraszek, Piotr Popik, Heidrun Potschka, Ernesto Prado Montes de Oca, Leonardo Restivo, Gernot Riedel, Merel Ritskes-Hoitinga, Janko Samardzic, Michael Schunn, Claudia Stöger, Vootele Voikar, Jan Vollert, Kimberley E. Wever, Kathleen Wuyts, Malcolm R. MacLeod, Ulrich Dirnagl, and Thomas Steckler. "Introduction to the Eqipd Quality System." eLife 10 (2021): e63294. https://dx.doi.org/10.7554/elife.63294 PMID - 34028353
Biedermann, Johann, Sebastian Braunbeck, Andrew J. R. Plested, and Han Sun. "Nonselective Cation Permeation in an Ampa-Type Glutamate Receptor." Proceedings of the National Academy of Sciences 118, no. 8 (2021): e2012843118. https://dx.doi.org/10.1073/pnas.2012843118 PMID - 33602810
Filippo, Roberto de, Benjamin R. Rost, Alexander Stumpf, Claire Cooper, John J. Tukker, Christoph Harms, Prateep Beed, and Dietmar Schmitz. "Somatostatin Interneurons Activated by 5-Ht2a Receptor Suppress Slow Oscillations in Medial Entorhinal Cortex." eLife 10 (2021): e66960. https://dx.doi.org/10.7554/elife.66960 PMID - 33789079.
Froehlich, Jonathan J., Bora Uyar, Margareta Herzog, Kathrin Theil, Petar Glažar, Altuna Akalin, and Nikolaus Rajewsky. "Parallel Genetics of Regulatory Sequences Using Scalable Genome Editing In vivo." Cell Reports 35, no. 2 (2021): 108988. https://dx.doi.org/10.1016/j.celrep.2021.108988 PMID - 33852857.
Gao, Xiaojie, Franziska Bender, Heun Soh, Changwan Chen, Mahsa Altafi, Sebastian Schütze, Matthias Heidenreich, Maria Gorbati, Mihaela-Anca Corbu, Marta Carus-Cadavieco, Tatiana Korotkova, Anastasios V. Tzingounis, Thomas J. Jentsch, and Alexey Ponomarenko. "Place Fields of Single Spikes in Hippocampus Involve Kcnq3 Channel-Dependent Entrainment of Complex Spike Bursts." Nature Communications 12, no. 1 (2021): 4801. https://dx.doi.org/10.1038/s41467-021-24805-2 PMID - 34376649.
Götz, Torsten W. B., Dmytro Puchkov, Veronika Lysiuk, Janine Lützkendorf, Alexander G. Nikonenko, Christine Quentin, Martin Lehmann, Stephan J. Sigrist, and Astrid G. Petzoldt. "Rab2 Regulates Presynaptic Precursor Vesicle Biogenesis at the Trans-Golgi." Journal of Cell Biology 220, no. 5 (2021): e202006040. https://dx.doi.org/10.1083/jcb.202006040 PMID - 33822845.
Harabula, Izabela, and Ana Pombo. "The Dynamics of Chromatin Architecture in Brain Development and Function." Current Opinion in Genetics & Development 67 (2021): 84-93. https://dx.doi.org/10.1016/j.gde.2020.12.008 PMID - 33421764.
Haucke, Volker. "A Mechanochemical Mechanism Couples Exocrine Secretion to Endocytic Membrane Retrieval." Developmental Cell 56, no. 11 (2021): 1557-59. https://dx.doi.org/10.1016/j.devcel.2021.05.012 PMID - 34102102.
Hofer, Sebastian J., YongTian Liang, Andreas Zimmermann, Sabrina Schroeder, Jörn Dengjel, Guido Kroemer, Tobias Eisenberg, Stephan J. Sigrist, and Frank Madeo. "Spermidine-Induced Hypusination Preserves Mitochondrial and Cognitive Function During Aging." Autophagy 17, no. 8 (2021): 1-3. https://dx.doi.org/10.1080/15548627.2021.1933299 PMID - 34105442.
Imbrosci, Barbara, Noam Nitzan, Sam McKenzie, José R. Donoso, Aarti Swaminathan, Claudia Böhm, Nikolaus Maier, and Dietmar Schmitz. "Subiculum as a Generator of Sharp Wave-Ripples in the Rodent Hippocampus." Cell Reports 35, no. 3 (2021): 109021. https://dx.doi.org/10.1016/j.celrep.2021.109021 PMID - 33882307.
Inak, Gizem, Agnieszka Rybak-Wolf, Pawel Lisowski, Tancredi M. Pentimalli, René Jüttner, Petar Glažar, Karan Uppal, Emanuela Bottani, Dario Brunetti, Christopher Secker, Annika Zink, David Meierhofer, Marie-Thérèse Henke, Monishita Dey, Ummi Ciptasari, Barbara Mlody, Tobias Hahn, Maria Berruezo-Llacuna, Nikos Karaiskos, Michela Di Virgilio, Johannes A. Mayr, Saskia B. Wortmann, Josef Priller, Michael Gotthardt, Dean P. Jones, Ertan Mayatepek, Werner Stenzel, Sebastian Diecke, Ralf Kühn, Erich E. Wanker, Nikolaus Rajewsky, Markus Schuelke, and Alessandro Prigione. "Defective Metabolic Programming Impairs Early Neuronal Morphogenesis in Neural Cultures and an Organoid Model of Leigh Syndrome." Nature Communications 12, no. 1 (2021): 1929. https://dx.doi.org/10.1038/s41467-021-22117-z PMID - 33771987.
Kreye, Jakob, Sukhvir K. Wright, Adriana van Casteren, Laura Stöffler, Marie-Luise Machule, S. Momsen Reincke, Marc Nikolaus, Scott van Hoof, Elisa Sanchez-Sendin, Marie A. Homeyer, César Cordero Gómez, Hans-Christian Kornau, Dietmar Schmitz, Angela M. Kaindl, Philipp Boehm-Sturm, Susanne Mueller, Max A. Wilson, Manoj A. Upadhya, Divya R. Dhangar, Stuart Greenhill, Gavin Woodhall, Paul Turko, Imre Vida, Craig C. Garner, Jonathan Wickel, Christian Geis, Yuko Fukata, Masaki Fukata, and Harald Prüss. "Encephalitis Patient-Derived Monoclonal Gabaa Receptor Antibodies Cause Epileptic Seizures." Journal of Experimental Medicine 218, no. 11 (2021): e20210012. https://dx.doi.org/10.1084/jem.20210012 PMID - 34546336.
Krude, Heiko, Stefan Mundlos, Nancy Christine Øien, Robert Opitz, and Markus Schuelke. "What Can Go Wrong in the Non-Coding Genome and How to Interpret Whole Genome Sequencing Data." medizinische genetik 33, no. 2 (2021): 121-31. https://dx.doi.org/10.1515/medgen-2021-2071.
Kuijpers, Marijn, and Volker Haucke. "Neuronal Autophagy Controls the Axonal Endoplasmic Reticulum to Regulate Neurotransmission in Healthy Neurons." Autophagy 17, no. 4 (2021): 1-3. https://dx.doi.org/10.1080/15548627.2021.1893569 PMID - 33615987.
Li, Ningfei, Barbara Hollunder, Juan Carlos Baldermann, Astrid Kibleur, Svenja Treu, Harith Akram, Bassam Al-Fatly, Bryan Strange, Juan A. Barcia, Ludvic Zrinzo, Eileen Joyce, Stephan Chabardes, Veerle Visser-Vandewalle, Mircea Polosan, Jens Kuhn, Andrea A. Kühn, and Andreas Horn. "A Unified Functional Network Target for Deep Brain Stimulation in Obsessive-Compulsive Disorder." Biological Psychiatry (2021). https://dx.doi.org/10.1016/j.biopsych.2021.04.006 PMID - 34134839.
Malek, Mouhannad, Anna M. Wawrzyniak, Peter Koch, Christian Lüchtenborg, Manuel Hessenberger, Timo Sachsenheimer, Wonyul Jang, Britta Brügger, and Volker Haucke. "Inositol Triphosphate-Triggered Calcium Release Blocks Lipid Exchange at Endoplasmic Reticulum-Golgi Contact Sites." Nature Communications 12, no. 1 (2021): 2673. https://dx.doi.org/10.1038/s41467-021-22882-x PMID - 33976123.
Orlando, Marta, Anton Dvorzhak, Felicitas Bruentgens, Marta Maglione, Benjamin R. Rost, Stephan J. Sigrist, Jörg Breustedt, and Dietmar Schmitz. "Recruitment of Release Sites Underlies Chemical Presynaptic Potentiation at Hippocampal Mossy Fiber Boutons." PLOS Biology 19, no. 6 (2021): e3001149. https://dx.doi.org/10.1371/journal.pbio.3001149 PMID - 34153028.
Pampaloni, Niccolò P., Irene Riva, Anna L. Carbone, and Andrew J. R. Plested. "Slow Ampa Receptors in Hippocampal Principal Cells." Cell Reports 36, no. 5 (2021): 109496. https://dx.doi.org/10.1016/j.celrep.2021.109496 PMID - 34348150.
Paraskevopoulou, Foteini, Poorya Parvizi, Gökçe Senger, Nurcan Tuncbag, Christian Rosenmund, and Ferah Yildirim. "Impaired Inhibitory Gabaergic Synaptic Transmission and Transcription Studied in Single Neurons by Patch-Seq in Huntington’s Disease." Proceedings of the National Academy of Sciences 118, no. 19 (2021): e2020293118. https://dx.doi.org/10.1073/pnas.2020293118 PMID - 33952696.
Patzke, Christopher, Jinye Dai, Marisa M. Brockmann, Zijun Sun, Pascal Fenske, Christian Rosenmund, and Thomas C. Südhof. "Cannabinoid Receptor Activation Acutely Increases Synaptic Vesicle Numbers by Activating Synapsins in Human Synapses." Molecular Psychiatry (2021): 1-16. https://dx.doi.org/10.1038/s41380-021-01095-0 PMID - 33931733.
Patzke, C., J. Dai, M. M. Brockmann, Z. Sun, P. Fenske, C. Rosenmund, and T. C. Sudhof. "Cb1 Receptor Activation Rapidly Alters Synaptic Vesicle Numbers in Mouse Hippocampal Synapses." Mol Psychiatry 26, no. 11 (Nov 2021): 6103. https://dx.doi.org/10.1038/s41380-021-01426-1.
Plested, Andrew J. R. "Nmda Receptors Singled out for Delayed Activation." Neuron 109, no. 3 (2021): 395-97. https://dx.doi.org/10.1016/j.neuron.2021.01.012 PMID - 33539773.
Pooryasin, Atefeh, Marta Maglione, Marco Schubert, Tanja Matkovic-Rachid, Sayed-mohammad Hasheminasab, Ulrike Pech, André Fiala, Thorsten Mielke, and Stephan J. Sigrist. "Unc13a and Unc13b Contribute to the Decoding of Distinct Sensory Information in Drosophila." Nature Communications 12, no. 1 (2021): 1932. https://dx.doi.org/10.1038/s41467-021-22180-6 PMID - 33771998.
Ramesh, Niraja, Marc J. F. Escher, Malou M. Mampell, Mathias A. Böhme, Torsten W. B. Götz, Pragya Goel, Tanja Matkovic, Astrid G. Petzoldt, Dion Dickman, and Stephan J. Sigrist. "Antagonistic Interactions between Two Neuroligins Coordinate Pre- and Postsynaptic Assembly." Current Biology 31, no. 8 (2021): 1711-25.e5. https://dx.doi.org/10.1016/j.cub.2021.01.093 PMID - 33651992.
Salih, Farid, Linda Schönborn, Siegfried Kohler, Christiana Franke, Martin Möckel, Thomas Dörner, Hans C. Bauknecht, Christian Pille, Jan A. Graw, Angelika Alonso, Johann Pelz, Hauke Schneider, Antonios Bayas, Monika Christ, Joji B. Kuramatsu, Thomas Thiele, Andreas Greinacher, and Matthias Endres. "Vaccine-Induced Thrombocytopenia with Severe Headache." New England Journal of Medicine (2021). https://dx.doi.org/10.1056/nejmc2112974 PMID - 34525282.
Sammons, Rosanna P., Alexandra Tzilivaki, and Dietmar Schmitz. "Oup Accepted Manuscript." Cerebral Cortex (2021). https://dx.doi.org/10.1093/cercor/bhab195 PMID - 34289029.
Santos, Miguel Rodríguez de los, Marion Rivalan, Friederike S. David, Alexander Stumpf, Julika Pitsch, Despina Tsortouktzidis, Laura Moreno Velasquez, Anne Voigt, Karl Schilling, Daniele Mattei, Melissa Long, Guido Vogt, Alexej Knaus, Björn Fischer-Zirnsak, Lars Wittler, Bernd Timmermann, Peter N. Robinson, Denise Horn, Stefan Mundlos, Uwe Kornak, Albert J. Becker, Dietmar Schmitz, York Winter, and Peter M. Krawitz. "A Crispr-Cas9–Engineered Mouse Model for Gpi-Anchor Deficiency Mirrors Human Phenotypes and Exhibits Hippocampal Synaptic Dysfunctions." Proceedings of the National Academy of Sciences 118, no. 2 (2021): e2014481118. https://dx.doi.org/10.1073/pnas.2014481118 PMID - 33402532.
Schroeder, Sabrina, Sebastian J. Hofer, Andreas Zimmermann, Raimund Pechlaner, Christopher Dammbrueck, Tobias Pendl, G. Mark Marcello, Viktoria Pogatschnigg, Martina Bergmann, Melanie Müller, Verena Gschiel, Selena Ristic, Jelena Tadic, Keiko Iwata, Gesa Richter, Aitak Farzi, Muammer Üçal, Ute Schäfer, Michael Poglitsch, Philipp Royer, Ronald Mekis, Marlene Agreiter, Regine C. Tölle, Péter Sótonyi, Johann Willeit, Barbara Mairhofer, Helga Niederkofler, Irmgard Pallhuber, Gregorio Rungger, Herbert Tilg, Michaela Defrancesco, Josef Marksteiner, Frank Sinner, Christoph Magnes, Thomas R. Pieber, Peter Holzer, Guido Kroemer, Didac Carmona-Gutierrez, Luca Scorrano, Jörn Dengjel, Tobias Madl, Simon Sedej, Stephan J. Sigrist, Bence Rácz, Stefan Kiechl, Tobias Eisenberg, and Frank Madeo. "Dietary Spermidine Improves Cognitive Function." Cell Reports 35, no. 2 (2021): 108985. https://dx.doi.org/10.1016/j.celrep.2021.108985 PMID - 33852843.
Schuelke, Markus. "Mutation Detection in the Non-Coding Genome." medizinische genetik 33, no. 2 (2021): 119-20. https://dx.doi.org/10.1515/medgen-2021-2070.
Schulz, Jan M., Jim W. Kay, Josef Bischofberger, and Matthew E. Larkum. "Gabab Receptor-Mediated Regulation of Dendro-Somatic Synergy in Layer 5 Pyramidal Neurons." Frontiers in Cellular Neuroscience 15 (2021): 718413. https://dx.doi.org/10.3389/fncel.2021.718413 PMID - 34512268.
Shin, Jiyun N., Doron, Guy, and Larkum, Matthew E. "Memories Off the Top of Your Head." Science 374, no. 6567 (Oct 29 2021): 538-39. https://dx.doi.org/10.1126/science.abk1859
Sobesky, Leon, Lukas Goede, Vincent J. J. Odekerken, Qiang Wang, Ningfei Li, Clemens Neudorfer, Nanditha Rajamani, Bassam Al-Fatly, Martin Reich, Jens Volkmann, Rob M. A. de Bie, Andrea A. Kühn, and Andreas Horn. "Subthalamic and Pallidal Deep Brain Stimulation: Are We Modulating the Same Network?", Brain (2021). https://dx.doi.org/10.1093/brain/awab258 PMID - 34453827.
Takahashi, Naoya, Sara Moberg, Timothy A. Zolnik, Julien Catanese, Robert N. S. Sachdev, Matthew E. Larkum, and Dieter Jaeger. "Thalamic Input to Motor Cortex Facilitates Goal-Directed Action Initiation." Current Biology 31, no. 18 (2021): 4148-55.e4. https://dx.doi.org/10.1016/j.cub.2021.06.089 PMID - 34302741.
Tukker, John J., Prateep Beed, Michael Brecht, Richard Kempter, Edvard I. Moser, and Dietmar Schmitz. "Microcircuits for Spatial Coding in the Medial Entorhinal Cortex." Physiological Reviews (2021). https://dx.doi.org/10.1152/physrev.00042.2020 PMID - 34254836.
Vardar, Gülçin, Andrea Salazar-Lázaro, Marisa M. Brockmann, Marion Weber-Boyvat, Sina Zobel, Victor Wumbor-Apin Kumbol, Thorsten Trimbuch, and Christian Rosenmund. "Reexamination of N-Terminal Domains of Syntaxin-1 in Vesicle Fusion from Central Murine Synapses." eLife 10 (2021): e69498. https://dx.doi.org/10.7554/elife.69498 PMID - 34427183.
Vierock, Johannes, Silvia Rodriguez-Rozada, Alexander Dieter, Florian Pieper, Ruth Sims, Federico Tenedini, Amelie C. F. Bergs, Imane Bendifallah, Fangmin Zhou, Nadja Zeitzschel, Joachim Ahlbeck, Sandra Augustin, Kathrin Sauter, Eirini Papagiakoumou, Alexander Gottschalk, Peter Soba, Valentina Emiliani, Andreas K. Engel, Peter Hegemann, and J. Simon Wiegert. "Bipoles Is an Optogenetic Tool Developed for Bidirectional Dual-Color Control of Neurons." Nature Communications 12, no. 1 (2021): 4527. https://dx.doi.org/10.1038/s41467-021-24759-5 PMID - 34312384.
Witkowska, Agata, and Volker Haucke. "Liquid-Like Protein Assemblies Initiate Endocytosis." Nature Cell Biology 23, no. 4 (2021): 301-02. https://dx.doi.org/10.1038/s41556-021-00665-2 PMID - 33820974.
Zhang, Yao, Ines Lahmann, Katharina Baum, Hiromi Shimojo, Philippos Mourikis, Jana Wolf, Ryoichiro Kageyama, and Carmen Birchmeier. "Oscillations of Delta-Like1 Regulate the Balance between Differentiation and Maintenance of Muscle Stem Cells." Nature Communications 12, no. 1 (2021): 1318. https://dx.doi.org/10.1038/s41467-021-21631-4 PMID - 33637744.
2020
Aru, J., M. Suzuki, and M. E. Larkum. "Cellular Mechanisms of Conscious Processing." Trends in Cognitive Sciences 24, no. 10 (Oct 2020): 814-25. https://dx.doi.org/10.1016/j.tics.2020.07.006.
Bayard, F., C. N. Thunell, C. Abe, R. Almeida, T. Banaschewski, G. Barker, A. L. W. Bokde, U. Bromberg, C. Buchel, E. B. Quinlan, S. Desrivieres, H. Flor, V. Frouin, H. Garavan, P. Gowland, A. Heinz, B. Ittermann, J. L. Martinot, M. L. P. Martinot, F. Nees, D. P. Orfanos, T. Paus, L. Poustka, P. Conrod, A. Stringaris, M. Struve, J. Penttila, V. Kappel, Y. Grimmer, T. Fadai, B. van Noort, M. N. Smolka, N. C. Vetter, H. Walter, R. Whelan, G. Schumann, P. Petrovic, and Imagen Consortium. "Distinct Brain Structure and Behavior Related to Adhd and Conduct Disorder Traits." Molecular Psychiatry 25, no. 11 (Nov 2020): 3020-33. https://dx.doi.org/10.1038/s41380-018-0202-6.
Beed, P., R. de Filippo, C. Holman, F. W. Johenning, C. Leibold, A. Caputi, H. Monyer, and D. Schmitz. "Layer 3 Pyramidal Cells in the Medial Entorhinal Cortex Orchestrate up-Down States and Entrain the Deep Layers Differentially." Cell Reports 33, no. 10 (Dec 2020). https://dx.doi.org/10.1016/j.celrep.2020.108470.
Broser, M., A. Spreen, P. E. Konold, E. Peter, S. Adam, V. Borin, I. Schapiro, R. Seifert, J. T. M. Kennis, Y. A. B. Sierra, and P. Hegemann. "Neor, a near-Infrared Absorbing Rhodopsin." Nature Communications 11, no. 1 (Nov 2020). https://dx.doi.org/10.1038/s41467-020-19375-8.
Clemens AM, Wang H, Brecht M. The lateral septum mediates kinship behavior in the rat. Nat Commun 2020, 11. http://dx.doi.org/10.1038/s41467-020-16489-x.
Dirnagl, U. "Institutions Can Retool to Make Research More Rigorous." Nature 588, no. 7837 (Dec 2020): 197-97. https://dx.doi.org/10.1038/d41586-020-02905-1.
Doron, G., J. N. Shin, N. Takahashi, M. Druke, C. Bocklisch, S. Skenderi, L. de Mont, M. Toumazou, J. Ledderose, M. Brecht, R. Naud, and M. E. Larkum. "Perirhinal Input to Neocortical Layer 1 Controls Learning." Science 370, no. 6523 (Dec 2020): 1435-+. https://dx.doi.org/10.1126/science.aaz3136.
Elias, G. J. B., A. Boutet, S. E. Joel, J. Germann, D. Gwun, C. Neudorfer, R. M. Gramer, M. Algarni, V. Paramanandam, S. Prasad, M. E. Beyn, A. Horn, R. Madhavan, M. Ranjan, C. S. Lozano, A. A. Kuhn, J. Ashe, W. Kucharczyk, R. P. Munhoz, P. Giacobbe, S. H. Kennedy, D. B. Woodside, S. K. Kalia, A. Fasano, M. Hodaie, and A. M. Lozano. "Probabilistic Mapping of Deep Brain Stimulation: Insights from 15 Years of Therapy." Annals of Neurology (https://dx.doi.org/10.1002/ana.25975).
Evangelista, R., G. Cano, C. Cooper, D. Schmitz, N. Maier, and R. Kempter. "Generation of Sharp Wave-Ripple Events by Disinhibition." Journal of Neuroscience 40, no. 41 (Oct 2020): 7811-36. https://dx.doi.org/10.1523/jneurosci.2174-19.2020
Gidon A, Zolnik TA, Fidzinski P, Bolduan F, Papoutsi A, Poirazi P, Holtkamp M, Vida I, Larkum ME. Dendritic action potentials and computation in human layer 2/3 cortical neurons. Science 2020, 367. http://dx.doi.org/10.1126/science.aax6239.
Heim C. Deficiency of Inflammatory Response to Acute Trauma Exposure as a Neuroimmune Mechanism Driving the Development of Chronic PTSD: Another Paradigmatic Shift for the Conceptualization of Stress-Related Disorders? Am J Psychiatry 2020, 177. http://dx.doi.org/10.1176/appi.ajp.2019.19111189.
Huang S, Piao C, Beuschel CB, Gotz T, Sigrist SJ. Presynaptic Active Zone Plasticity Encodes Sleep Need in Drosophila. Curr Biol 2020. http://dx.doi.org/10.1016/j.cub.2020.01.019.
Irmen F, Horn A, Mosley P, Perry A, Petry-Schmelzer JN, Dafsari HS, Barbe M, Visser-Vandewalle V, Schneider GH, Li N, Kubler D, Wenzel G, Kuhn A. Left prefrontal impact links subthalamic stimulation with depressive symptoms. Ann Neurol 2020. http://dx.doi.org/10.1002/ana.25734.
Kempfer R, Pombo A. Methods for mapping 3D chromosome architecture. Nat Rev Genet 2020, 21. http://dx.doi.org/10.1038/s41576-019-0195-2.
Kim, M., V. Franke, B. Brandt, E. D. Lowenstein, V. Schowel, S. Spuler, A. Akalin, and C. Birchmeier. "Single-Nucleus Transcriptomics Reveals Functional Compartmentalization in Syncytial Skeletal Muscle Cells." Nature Communications 11, no. 1 (Dec 2020). https://dx.doi.org/10.1038/s41467-020-20064-9.
Kornau HC, Kreye J, Stumpf A, Fukata Y, Parthier D, Sammons RP, Imbrosci B, Kurpjuweit S, Kowski AB, Fukata M, Pruss H, Schmitz D. Human Cerebrospinal Fluid Monoclonal LGI1 Autoantibodies Increase Neuronal Excitability. Ann Neurol 2020, 87. http://dx.doi.org/10.1002/ana.25666.
Kouwenhoven, W. M., G. Fortin, A. M. Penttinen, C. Florence, B. Delignat-Lavaud, M. J. Bourque, T. Trimbuch, M. P. Luppi, A. Salvail-Lacoste, P. Legault, J. F. Poulin, C. Rosenmund, R. Awatramani, and L. E. Trudeau. "Vglut2 Expression in Dopamine Neurons Contributes to Postlesional Striatal Reinnervation." Journal of Neuroscience 40, no. 43 (Oct 2020): 8262-75. https://dx.doi.org/10.1523/jneurosci.0823-20.2020.
Kreye, J., S. M. Reincke, H. C. Kornau, E. Sanchez-Sendin, V. M. Corman, H. J. Liu, M. Yuan, N. C. Wu, X. Y. Zhu, C. C. D. Lee, J. Trimpert, M. Holtje, K. Dietert, L. Stoffler, N. von Wardenburg, S. van Hoof, M. A. Homeyer, J. Hoffmann, A. Abdelgawad, A. D. Gruber, L. D. Bertzbach, D. Vladimirova, L. Y. Li, P. C. Barthel, K. Skriner, A. C. Hocke, S. Hippenstiel, M. Witzenrath, N. Suttorp, F. Kurth, C. Franke, M. Endres, D. Schmitz, L. M. Jeworowski, A. Richter, M. L. Schmidt, T. Schwarz, M. A. Muller, C. Drosten, D. Wendisch, L. E. Sander, N. Osterrieder, I. A. Wilson, and H. Pruss. "A Therapeutic Non-Self-Reactive Sars-Cov-2 Antibody Protects from Lung Pathology in a Covid-19 Hamster Model." Cell 183, no. 4 (Nov 2020): 1058-+. https://dx.doi.org/10.1016/j.cell.2020.09.049.
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Kurreck, C., E. Castanos-Velez, D. Freyer, S. Blumenau, I. Przesdzing, R. Bernard, and U. Dirnagl. "Improving Quality of Preclinical Academic Research through Auditing: A Feasibility Study." Plos One 15, no. 10 (Oct 2020). https://dx.doi.org/10.1371/journal.pone.0240719.
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Rozenberg, A., J. Oppermann, J. Wietek, R. G. F. Lahore, R. A. Sandaa, G. Bratbak, P. Hegemann, and O. Beja. "Lateral Gene Transfer of Anion-Conducting Channelrhodopsins between Green Algae and Giant Viruses." Current Biology 30, no. 24 (Dec 2020): 4910-+. https://dx.doi.org/10.1016/j.cub.2020.09.056.
Sawade L, Grandi F, Mignanelli M, Patino-Lopez G, Klinkert K, Langa-Vives F, Di Guardo R, Echard A, Bolino A, Haucke V. Rab35-regulated lipid turnover by myotubularins represses mTORC1 activity and controls myelin growth. Nat Commun 2020, 11. http://dx.doi.org/10.1038/s41467-020-16696-6. Volkers Affiliation is NeuroCure
Schlunk, F., P. Fischer, H. M. G. Princen, A. Rex, V. Prinz, M. Foddis, D. Lutjohann, U. Laufs, and M. Endres. "Effects of Inhibition or Deletion of Pcsk9 (Proprotein Convertase Subtilisin/Kexin Type 9) on Intracerebral Hemorrhage Volumes in Mice." Stroke 51, no. 11 (Nov 2020): E297-E98. https://dx.doi.org/10.1161/strokeaha.120.030087.
Shen, C., Q. Luo, T. Y. Jia, Q. Zhao, S. Desrivieres, E. B. Quinlan, T. Banaschewski, S. Millenet, A. L. W. Bokde, C. Buchel, H. Flor, V. Frouin, H. Garavan, P. Gowland, A. Heinz, B. Ittermann, J. L. Martinot, E. Artiges, M. L. Paillere-Martinot, F. Nees, D. P. Orfanos, T. Paus, L. Poustka, J. H. Frohner, M. N. Smolka, H. Walter, R. Whelan, F. Li, J. F. Feng, G. Schumann, B. J. Sahakian, and Imagen Consortium. "Neural Correlates of the Dual-Pathway Model for Adhd in Adolescents." American Journal of Psychiatry 177, no. 9 (Sep 2020): 844-54. https://dx.doi.org/10.1176/appi.ajp.2020.19020183.
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2019
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Carmona-Gutierrez D*, Zimmermann A*, Kainz K, Pietrocola F, Chen G, Maglioni S, Schiavi A, Nah J, Mertel S, Beuschel CB, Castoldi F, Sica V, Trausinger G, Raml R, Sommer C, Schroeder S, Hofer SJ, Bauer MA, Pendl T, Tadic J, Dammbrueck C, Hu Z, Ruckenstuhl C, Eisenberg T, Durand S, Bossut N, Aprahamian F, Abdellatif M, Sedej S, Enot DP, Wolinski H, Dengjel J, Kepp O, Magnes C, Sinner F, Pieber TR, Sadoshima J, Ventura N, Sigrist SJ, Kroemer G, Madeo F. The flavonoid 4,4'-dimethoxychalcone promotes autophagy-dependent longevity across species. Nat Commun 2019, 10. http://dx.doi.org/10.1038/s41467-019-08555-w. | * These authors contributed equally.
Clemens AM, Lenschow C, Beed P, Li L, Sammons R, Naumann RK, Wang H, Schmitz D, Brecht M. Estrus-Cycle Regulation of Cortical Inhibition. Curr. Biol. 2019, 29. http://dx.doi.org/10.1016/j.cub.2019.01.045.
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Eigenbrod O*, Debus KY*, Reznick J, Bennett NC, Sanchez-Carranza O, Omerbasic D, Hart DW, Barker AJ, Zhong W, Lutermann H, Katandukila JV, Mgode G, Park TJ, Lewin GR. Rapid molecular evolution of pain insensitivity in multiple African rodents. Science 2019, 364. http://dx.doi.org/10.1126/science.aau0236. | * These authors contributed equally.
Fenske P*, Grauel MK*, Brockmann MM, Dorrn AL, Trimbuch T, Rosenmund C. Autaptic cultures of human induced neurons as a versatile platform for studying synaptic function and neuronal morphology. Sci. Rep. 2019, 9. http://dx.doi.org/10.1038/s41598-019-41259-1. | * These authors contributed equally.
Goppner C*, Orozco IJ*, Hoegg-Beiler MB, Soria AH, Hubner CA, Fernandes-Rosa FL, Boulkroun S, Zennaro MC, Jentsch TJ. Pathogenesis of hypertension in a mouse model for human CLCN2 related hyperaldosteronism. Nat Commun 2019, 10. http://dx.doi.org/10.1038/s41467-019-12113-9. | * These authors contributed equally.
Heinz A, Zhao X‡, Liu S‡. Implications of the Association of Social Exclusion With Mental Health. JAMA Psychiatry 2019. http://dx.doi.org/10.1001/jamapsychiatry.2019.3009. | ‡ Co-corresponding authors.
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Houtman J, Freitag K, Gimber N, Schmoranzer J, Heppner FL*, Jendrach M*. Beclin1-driven autophagy modulates the inflammatory response of microglia via NLRP3. EMBO J. 2019, 38. http://dx.doi.org/10.15252/embj.201899430. | * These authors contributed equally.
Kempfer R‡, Pombo A‡. Methods for mapping 3D chromosome architecture. Nat. Rev. Genet. 2019. http://dx.doi.org/10.1038/s41576-019-0195-2. | ‡ Co-corresponding authors.
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Lehmann M‡, Lukonin I, Noe F, Schmoranzer J, Clementi C, Loerke D, Haucke V‡. Nanoscale coupling of endocytic pit growth and stability. Sci Adv 2019, 5. http://dx.doi.org/10.1126/sciadv.aax5775. | ‡ Co-corresponding authors
Nitzan M*, Karaiskos N*, Friedman N‡, Rajewsky N‡. Gene expression cartography. Nature 2019, 576. http://dx.doi.org/10.1038/s41586-019-1773-3. | * These authors contributed equally; ‡ co-corresponding authors.
Patzke C*, Brockmann MM*, Dai J*, Gan KJ, Grauel MK, Fenske P, Liu Y, Acuna C, Rosenmund C, Sudhof TC. Neuromodulator Signaling Bidirectionally Controls Vesicle Numbers in Human Synapses. Cell 2019, 179. http://dx.doi.org/10.1016/j.cell.2019.09.011. | * These authors contributed equally.
Quade B*, Camacho M*, Zhao X, Orlando M, Trimbuch T, Xu J, Li W, Nicastro D, Rosenmund C‡, Rizo J‡. Membrane bridging by Munc13-1 is crucial for neurotransmitter release. Elife 2019, 8. http://dx.doi.org/10.7554/eLife.42806. | * These authors contributed equally; ‡ co-corresponding authors.
Reinhold AS*, Sanguinetti-Scheck JI*, Hartmann K*, Brecht M. Behavioral and neural correlates of hide-and-seek in rats. Science 2019, 365. http://dx.doi.org/10.1126/science.aax4705. | * These authors contributed equally.
Skourti-Stathaki K‡, Torlai Triglia E, Warburton M, Voigt P, Bird A, Pombo A‡. R-Loops Enhance Polycomb Repression at a Subset of Developmental Regulator Genes. Mol. Cell 2019, 73. http://dx.doi.org/10.1016/j.molcel.2018.12.016. | ‡ Co-corresponding authors.
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Wallroth A, Koch PA, Marat AL, Krause E, Haucke V. Protein kinase N controls a lysosomal lipid switch to facilitate nutrient signalling via mTORC1. Nat. Cell Biol. 2019, 21. http://dx.doi.org/10.1038/s41556-019-0377-3.
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2018
Ast, A., A. Buntru, F. Schindler, R. Hasenkopf, A. Schulz, L. Brusendorf, K. Klockmeier, G. Grelle, B. McMahon, H. Niederlechner, I. Jansen, L. Diez, J. Edel, A. Boeddrich, S. A. Franklin, B. Baldo, S. Schnoegl, S. Kunz, B. Purfurst, A. Gaertner, H. H. Kampinga, A. J. Morton, A. Petersen, J. Kirstein, G. P. Bates, and E. E. Wanker. "Mhtt Seeding Activity: A Marker of Disease Progression and Neurotoxicity in Models of Huntington's Disease." Molecular Cell 71, no. 5 (Sep 2018): 675-+. http://dx.doi.org/10.1016/j.molcel.2018.07.032.
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Bernal Sierra, Y. A., B. R. Rost, M. Pofahl, A. M. Fernandes, R. A. Kopton, S. Moser, D. Holtkamp, N. Masala, P. Beed, J. J. Tukker, S. Oldani, W. Bonigk, P. Kohl, H. Baier, F. Schneider-Warme, P. Hegemann, H. Beck, R. Seifert, and D. Schmitz. "Potassium Channel-Based Optogenetic Silencing." Nat Commun 9, no. 1 (Nov 5 2018): 4611. http://dx.doi.org/10.1038/s41467-018-07038-8.
Blecharz-Lang, K. G., J. Wagner, A. Fries, M. Nieminen-Kelha, J. Rosner, U. C. Schneider, and P. Vajkoczy. "Interleukin 6-Mediated Endothelial Barrier Disturbances Can Be Attenuated by Blockade of the Il6 Receptor Expressed in Brain Microvascular Endothelial Cells." Translational Stroke Research 9, no. 6 (Dec 2018): 631-42. https://doi.org/10.1007/s12975-018-0614-2.
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Chang, H. D., K. Tokoyoda, and A. Radbruch. "Immunological Memories of the Bone Marrow." Immunological Reviews 283, no. 1 (May 2018): 86-98. https://doi.org/10.1111/imr.12656.
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2016
Accolla, E. A., M. Herrojo Ruiz, A. Horn, G. H. Schneider, T. Schmitz-Hubsch, B. Draganski, and A. A. Kuhn. "Brain Networks Modulated by Subthalamic Nucleus Deep Brain Stimulation." Brain 139, no. Pt 9 (Sep 2016): 2503-15. http://dx.doi.org/10.1093/brain/aww182.
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Bayerl, S. H., R. Niesner, Z. Cseresnyes, H. Radbruch, J. Pohlan, S. Brandenburg, M. A. Czabanka, and P. Vajkoczy. "Time Lapse in Vivo Microscopy Reveals Distinct Dynamics of Microglia-Tumor Environment Interactions - a New Role for the Tumor Perivascular Space as Highway for Trafficking Microglia." Glia (May 3 2016). http://dx.doi.org/10.1002/glia.22994.
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Booker, S. A., D. Althof, A. Gross, D. Loreth, J. Muller, A. Unger, B. Fakler, A. Varro, M. Watanabe, M. Gassmann, B. Bettler, R. Shigemoto, I. Vida, and A. Kulik. "Kctd12 Auxiliary Proteins Modulate Kinetics of Gabab Receptor-Mediated Inhibition in Cholecystokinin-Containing Interneurons." Cereb Cortex (Apr 12 2016). http://dx.doi.org/10.1093/cercor/bhw090.
Brandenburg, S., A. Muller, K. Turkowski, Y. T. Radev, S. Rot, C. Schmidt, A. D. Bungert, G. Acker, A. Schorr, A. Hippe, K. Miller, F. L. Heppner, B. Homey, and P. Vajkoczy. "Resident Microglia Rather Than Peripheral Macrophages Promote Vascularization in Brain Tumors and Are Source of Alternative Pro-Angiogenic Factors." Acta Neuropathologica 131, no. 3 (Mar 2016): 365-78. http://dx.doi.org/10.1007/s00401-015-1529-6.
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Takahashi, N., T. G. Oertner, P. Hegemann, and M. E. Larkum. "Active Cortical Dendrites Modulate Perception." Science 354, no. 6319 (Dec 23 2016): 1587-90. http://dx.doi.org/10.1126/science.aah6066.
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2015
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Caspari, F., V. J. Baumann, E. Garcia-Pino, and U. Koch. "Heterogeneity of Intrinsic and Synaptic Properties of Neurons in the Ventral and Dorsal Parts of the Ventral Nucleus of the Lateral Lemniscus." Front Neural Circuits 9 (2015): 74. http://dx.doi.org/10.3389/fncir.2015.00074.
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Frank, J. A., M. Moroni, R. Moshourab, M. Sumser, G. R. Lewin, and D. Trauner. "Photoswitchable Fatty Acids Enable Optical Control of Trpv1." Nat Commun 6 (2015): 7118. http://dx.doi.org/10.1038/ncomms8118.
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Johenning, F. W., A. K. Theis, U. Pannasch, M. Ruckl, S. Rudiger, and D. Schmitz. "Ryanodine Receptor Activation Induces Long-Term Plasticity of Spine Calcium Dynamics." PLoS Biol 13, no. 6 (Jun 2015): e1002181. http://dx.doi.org/10.1371/journal.pbio.1002181.
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Kirstein, J., D. Morito, T. Kakihana, M. Sugihara, A. Minnen, M. S. Hipp, C. Nussbaum-Krammer, P. Kasturi, F. U. Hartl, K. Nagata, and R. I. Morimoto. "Proteotoxic Stress and Ageing Triggers the Loss of Redox Homeostasis across Cellular Compartments." EMBO J 34, no. 18 (Sep 14 2015): 2334-49. http://dx.doi.org/10.15252/embj.201591711.
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2014
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2013
Ebstein, F., A. Voigt, N. Lange, A. Warnatsch, F. Schroter, T. Prozorovski, U. Kuckelkorn, O. Aktas, U. Seifert, P. M. Kloetzel, and E. Kruger. "Immunoproteasomes Are Important for Proteostasis in Immune Responses." Cell 152, no. 5 (Feb 28 2013): 935-7. http://dx.doi.org/10.1016/j.cell.2013.02.018.
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2012
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2011
Burgalossi, A., L. Herfst, M. von Heimendahl, H. Forste, K. Haskic, M. Schmidt, and M. Brecht. "Microcircuits of Functionally Identified Neurons in the Rat Medial Entorhinal Cortex." Neuron 70, no. 4 (May 26 2011): 773-86. http://dx.doi.org/10.1016/j.neuron.2011.04.003.
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2010
Beed, P., M. H. Bendels, H. F. Wiegand, C. Leibold, F. W. Johenning, and D. Schmitz. "Analysis of Excitatory Microcircuitry in the Medial Entorhinal Cortex Reveals Cell-Type-Specific Differences." Neuron 68, no. 6 (Dec 22 2010): 1059-66. http://dx.doi.org/10.1016/j.neuron.2010.12.009.
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2009
Alle, H., A. Roth, and J. R. Geiger. "Energy-Efficient Action Potentials in Hippocampal Mossy Fibers." Science 325, no. 5946 (Sep 11 2009): 1405-8. http://dx.doi.org/10.1126/science.1174331.
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2008
Ehrnhoefer, D. E., J. Bieschke, A. Boeddrich, M. Herbst, L. Masino, R. Lurz, S. Engemann, A. Pastore, and E. E. Wanker. "Egcg Redirects Amyloidogenic Polypeptides into Unstructured, Off-Pathway Oligomers." Nat Struct Mol Biol 15, no. 6 (Jun 2008): 558-66. http://dx.doi.org/10.1038/nsmb.1437.
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